Effect of netra Seka with Saindhava Lavana Siddha Sheetala Jala & Goksheera in the Management of Shushkaakshipaaka Dry Eye Syndrome A Randomized Controlled Clinical Trial
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The effect of Saindhava Lavana Seka might be helping in reducing inflammation and hence restoration function of goblet cells and mucin secreting cells of conjunctiva might restore functioning normally
研究概览
简要总结
Yet to start clinical trialWatering in the eyeitself is one of the clinical features of Dry Eye Syndrome, which is actually areflex watering, induced due to dryness. This phenomenon keeps the patient awayfrom the doctor and makes the disease chronic. In early stages, clear wateringoccurs, whereas in due course these secretions become turbid and turns intomucoid with filamental debris (i.e. increased osmolarity of tears with inflammatoryocular surface disorder).
Tear deficiency,evaporative troubles, altered food – behavioural regimen, profession andmodified life style contribute a lot for this trouble. In modern medicine, Dry Eye Syndrome is palliativemanageable condition. Selection of the particular tear supplement is the onlynon-invasive treatment.
In present era no oneis having enough time and patience to go for lengthy procedures like Nasya,Anjana, Aschyotana, Tarpana, etc for the non-acute conditions like Dry EyeSyndrome.
Hence, there is greatneed of safe, effective, short-term, easily available and that can be done easily.Ghritamanda Aschyotana is one of such procedure which mimics as modernmanagement and easily acceptable procedure.
Saindhava Lavana ishaving Kapha Lekhana, Shodhana,Kledahara, Chaakshushya and Shothaharaproperty. It is being used as an ingredient of many ocular pharmaceutical preparations.
Considering all above,this study is planned to find the comparative efficacy of Saindhava Lavana Siddha Sheetala Jala & Goksheera in the management of Shushkaakshipaakawith special reference to Dry Eye Syndrome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Open Label
入排标准
- 年龄范围
- 20.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •1Patients fulfilling the diagnostic criteria of Shushkaakshipaaka (Dry Eye Syndrome) 220 to 40 years of age group 3Irrespective of sex occupation religion will be included.
排除标准
- •ïƒ˜Age less than 20 years and more than 40 years Severe conditions like Steven Johnson’s syndrome, Chemical-Thermal-Radiation burns, idiopathic atrophy, Trachoma, Ocular pemphigoid Corneal epitheliopathies like Neuroparalytic keratitis, post-herpatic / post-measles infection of cornea, Conjunctival epitheliopathies like Pterygium, Pseudo-pterygium, Tumours, Retention cysts, chronic low grade bacterial / viral conjunctivitis Lid abnormalities like Meibominitis, Blepharitits, Facial nerve palsy, Lagophthalmous, Lacrimal gland diseases like infiltration of gland with sarcoidosis, lymphoma, leukemia and amyloidosis, congenital Alacrima Vitamin A deficiency, effect of the drugs like atropine, antihistamine, diuretics Specific systemic infections like Tuberculosis, Leprosy, Hypertension, RA, Diabetes mellitus, etc.
结局指标
主要结局
The effect of Saindhava Lavana Seka might be helping in reducing inflammation and hence restoration function of goblet cells and mucin secreting cells of conjunctiva might restore functioning normally
时间窗: 1 Week
Thus might restore moisture and health of ocular surface
时间窗: 1 Week
次要结局
- Due to expected normalcy the tear film components and tear fluid quantity and pattern of flow may restore(1 week)