NCT01069224Unknown不适用
Analysis of Proinflammatory Factors in the Synovial Fluid In Patients With Rotator Cuff Disease
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 主要终点
- cytokines and MMP's levels in patients with RC pathology and in control group
研究概览
简要总结
Role of proinflammatory factors in Patients with Rotator Cuff Disease
Objective:
To measure the levels of various cytokines and metalloproteases in patients with rotator cuff disease, and control group and to determine the correlations among them.
详细描述
We hypothesize that cytokines and MMP's level will be significantly higher in patients with RC pathology than in control group and will be related to the time frame since injury (i.e. - higher levels as close to the injury). In addition we will examine possible relation of those levels to the pain curve by using Visual Analogue Scale.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ability to understand and accept the trial procedures and to sign an informed consent form in accordance with national legislation.
- •Patients between age 18-65 scheduled for a surgery in a Shoulder unit
- •Patients suffering from Rotator Cuff Disease
- •Patients suffering from any noninflammatory shoulder condition which requires surgical intervention
排除标准
- •Revision rotator cuff repair
- •Recurrent shoulder surgery
- •Psychiatric illness
- •Inflammatory condition.
- •Current use of anti-inflammatory drugs.
- •Previous or current shoulder infection.
结局指标
主要结局
cytokines and MMP's levels in patients with RC pathology and in control group
时间窗: 12 month
次要结局
- Levels of pain curve by using Visual Analogue Scale(12 month)
研究者
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