Liver Transplantation From Living Donors For Treatment Of Non-Resectable Colorectal Carcinoma Liver Metastases: A Registry Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- percentage overall survival
研究概览
简要总结
The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.
详细描述
The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.
Our primary outcome of interest was the OS and recurrence-free survival (RFS) of patients who underwent LDLT at our center.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Non-amenable to curative hepatic resection as defined by FLR <30%
- •Histologically confirmed adenocarcinoma of the colon or rectum
- •Candidate for LDLT for colorectal liver metastasis per the University of Rochester liver transplant program
排除标准
- •Not a candidate of the LDLT liver transplant protocol for treatment of colorectal liver metastasis.
- •Unwilling to consent
结局指标
主要结局
percentage overall survival
时间窗: 5 years
OS proportions to be calculated at 1, 3, and 5 years with Kaplan Meier analysis
percentage of patients with recurrence free survival
时间窗: 5 years
RFS proportions to be calculated at 1, 3, and 5 years with Kaplan Meier analysis
次要结局
未报告次要终点
研究者
Roberto Hernandez-Alejandro
Professor
University of Rochester