Identification of Viral Variants Involved in the Transmission of Hepatitis C and Characterization of Antigenic and Functional Properties of Their Envelope Glycoproteins
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- HCV serological markers
研究概览
简要总结
The study consists to Identify viral variants involved in the transmission of hepatitis C and characterize the antigenic and functional properties of their envelope glycoproteins at very early stage of infection (before seroconversion).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age > 18 years
- •agree to participate in this study (signing the consent form or information form signed and letter of no objection for subjects contaminated by blood exposure).
- •These criteria are specific to contaminated subjects:
- •primary infection before development of HCV antibody (seroconversion): nucleic acid testing positive in the absence of HCV antibodies.
- •These criteria are specific to individual sources :
- •HCV antibody positive.
排除标准
- •refusal to participate
- •private about freedom
- •under guardianship
- •under justice
- •minor or major person unable to consent
研究组 & 干预措施
Retrospective cases
Population of infected blood donors in 2007, 2008 and 2009 No blood sample
Recently infected subjects
Actual population of blood donors primo-infected with HCV with specific intervention for the study : one blood sample during the inclusion visit
干预措施: Blood sample (act specific of blood withdrawal for the study) (Procedure)
Individuals sources
Specific intervention for the study : one blood sample during the inclusion visit
干预措施: Blood sample (act specific of blood withdrawal for the study) (Procedure)
结局指标
主要结局
HCV serological markers
时间窗: up to 30 months
Immunoblot analysis from blood samples collected during the study
次要结局
未报告次要终点