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临床试验/CTRI/2012/11/003085
CTRI/2012/11/003085已完成不适用

Vitamin D deficiency in postmenopausal women with pelvic floor disorders

christian medical college hospital1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2011年1月2日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
120
试验地点
1
主要终点
Association of Vitamin D deficiency and pelvic floor disorders- (Prolapse and stress urinary incontinence)

研究概览

简要总结

INTRODUCTION

Pelvic floor disorders (PFD) is a group of disorders including pelvic organ prolapse (POP), urinary incontinence (UI) and fecal incontinence . Recent studies show the role of vitamin D in muscle strength and neuromuscular function . The various factors contributing to pelvic floor disorders include multiparity, mode of delivery, instrumental delivery, obesity, aging, collagen defects and menopause. This indicates that postmenopausal women are more likely to develop symptoms of PFD. Elderly women are more likely to be vitamin D deficient due to the reduced activity of the skin to convert 25 hydroxy cholecalciferol to active form as the age advances . In this study we intend to evaluate the possible association of vitamin D deficiency and pelvic floor disorders especially POP and UI in postmenopausal women. METHODS 60 women in the control group formed by postmenopausal women without signs and symptoms of prolapse or stress urinary incontinece and 60 postmenopausal women in the case group with signs or symptoms of pelvic floor disorders were included.Women with chronic renal illness, previous vitamin D supplementation, non ambulant chronically bed ridden patients were excluded from the study. Serum vitamin D levels were measured at the time of recruitment in both the groups and proforma containing detailed history for risk factors of vitamin D deficiency and pelvic floor disorders was completed. The data analyzed by SPSS software.

研究设计

研究类型
Observational

入排标准

年龄范围
40.00 Year(s) 至 75.00 Year(s)(—)
性别
Female

入选标准

  • Postmenopausal women without symptoms or signs of prolapse/ stress urinary incontinence formed the control group and postmenopausal women with symptoms or signs of prolapse and urinary incontinence formed the cases.

排除标准

  • Previously treated with vitamin D supplementation
  • Chronic renal disease.
  • Bed ridden patients.

结局指标

主要结局

Association of Vitamin D deficiency and pelvic floor disorders- (Prolapse and stress urinary incontinence)

时间窗: At the time of recruitment

次要结局

  • Vitamin D deficiency prevalence in the postmenopausal women(At the time of recruitment)

研究者

申办方类型
Private medical college

研究点 (1)

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