NCT02814032招募中不适用
Differences Protein Expression in Papillary Thyroid Carcinoma
The Affiliated Hospital of Inner Mongolia Medical University1 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2016年6月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- differences in protein expression
研究概览
简要总结
Thyroid carcinoma is the common endocrine system malignant neoplasm. At present it has become the malignant neoplasm of fastest growing incidence rate. More than 85% thyroid carcinoma is papillary thyroid carcinoma. Cervical lymph node metastasis is common in papillary thyroid carcinoma patients. This study aim to reveal protein expression differences between papillary thyroid carcinoma with cervical lymph node metastasis and without cervical lymph node metastasis.
详细描述
- Object: Patients aged 18-65 years; newly diagnosed papillary thyroid carcinoma with cervical lymph node metastasis and without cervical lymph node metastasis and undergone thyroidectomy according to the China thyroid association guidelines for the Management of thyroid nodule and thyroid cancer.
- Clinical information, examination data: Information is obtained from medical record abstraction.
- Samples: Fresh frozen thyroid tissues from each sample group(normal histology, benign disease, papillary thyroid carcinoma with cervical lymph node metastasis, papillary thyroid carcinoma without cervical lymph node metastasis ).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Newly diagnosed papillary thyroid carcinoma.
- •Undergo thyroidectomy according to the China thyroid association guidelines forthe Management of thyroid nodule and thyroid cancer.
排除标准
- •Current substance abuse/dependence.
- •Daily tobacco and alcohol use.
- •Whole neck irradiation or surgery.
- •Prior cancer diagnosis or chemotherapy treatment.
- •Active autoimmune disorder.
- •Uncontrolled allergic condition or asthma.
- •Chronic use of oral steroid medication.
- •Hormone therapy (estrogen, progestin compounds).
结局指标
主要结局
differences in protein expression
时间窗: 6 months
次要结局
未报告次要终点
研究者
研究点 (1)
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