Comparison of Two-hand Mask Ventilation Technique: Standard V-E Versus Reversal V-E Technique
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 92
- 试验地点
- 1
- 主要终点
- Visual score of friendliness of mask holding technique using 11 point scale
研究概览
简要总结
This study hypothesizes that a novel reversal V-E ventilation technique will retain its high efficiency as that of standard V-E technique and will be easier to use.
详细描述
Despite advances in intubation technology, difficult airways persist. Because it is failure to oxygenate, not failure to intubate, that ultimately leads to brain injury and cardiovascular collapse, effective mask ventilation is at least as important as successful intubation. Therefore optimizing mask ventilation is crucial for clinicians. When difficult mask ventilation encounters, clinicians often switch to two hand technique to hold the mask including either "C-E" clamp or "V-E" clamp. Both volume mode ventilation and pressure mode ventilation are superior with the V-E technique as compared to the C-E technique. The study will test the hypothesis that a novel reversal V-E mask ventilation technique will retain its high efficiency as that of standard V-E technique but be easier to use than standard V-E technique.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Over 18 years of age
- •Requiring general anesthesia
- •BMI =>30
排除标准
- •Untreated ischemic heart diseases
- •Respiratory disorders, including COPD and asthma
- •American Society of Anesthesiologists(ASA) physical class of 4 or greater
- •Undergoing emergency surgery
- •Requiring rapid sequence intubation for aspiration protection
- •Non propofol - induction of anesthesia
- •Requiring fiberoptic intubation
- •Pregnant women or women who have given birth within the last month
研究组 & 干预措施
Standard V-E ventilation technique
After induction of anesthesia subject will be ventilated using the standard V-E ventilation technique. Ventilation will be carried out using pressure mode ventilation at respiratory rate of 10 breaths per minute, I:E ratio of 1:2, peak inspiratory pressure of 20cmH2O and no PEEP. If the subjects can be adequately ventilated, as defined by perceivable chest movement and end tidal CO2 during the first three breaths, ventilation will continue for total ten breaths.
干预措施: Standard V-E ventilation technique (Procedure)
Reversal V-E ventilation technique
After induction of anesthesia subject will be ventilated using the reversal V-E ventilation technique. Ventilation will be carried out using pressure mode ventilation at respiratory rate of 10 breaths per minute, I:E ratio of 1:2, peak inspiratory pressure of 20cmH2O and no PEEP. If the subjects can be adequately ventilated, as defined by perceivable chest movement and end tidal CO2 during the first three breaths, ventilation will continue for total ten breaths.
干预措施: Reversal V-E ventilation technique (Procedure)
结局指标
主要结局
Visual score of friendliness of mask holding technique using 11 point scale
时间窗: Conclusion of masked ventilation (approximately 5 minutes)
Visual score of friendliness of mask holding technique using 11 point scale when 0 is easy and 10 is difficult.
次要结局
- AUC of exhaled tidal volume (Vt) trace(Period of masked ventilation (approximately 5 minutes))
- Peak inspiratory airway pressure(Period of masked ventilation (approximately 5 minutes))
- Vt/AUC(Period of masked ventilation (approximately 5 minutes))
研究者
Christopher Canlas
Assistant Professor
Vanderbilt University Medical Center