IRCT20180228038899N1招募中2 期
Evaluation of safety and efficacy of Allogenic Mesenchymal Stem Cell transplantation (core matrix extracted)in Late-Onset Neurometabolic disorders: an open label study
Pasture Institute of Iran0 个研究点目标入组 25 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 40 years（—）
- 性别
- All
入选标准
- •The definitive diagnosis of neurometabolic diseases leads to ataxia, leukodystrophy,Myopathy or Neuropathy based on laboratory findings of molecular genetics
- •Age between 18-40 years old
- •Written consent of the patient and parents to attend the study
- •Normal routine biochemistry, hematology and negative serology and virology tests
- •Negative Tumor survey includes abdominal and pelvic ultrasonography and prostatic and breast and thyroid ,and occult blood in the stool test
排除标准
- •A pregnant woman (positive pregnancy test) or a nursing or illness who is planning a pregnancy during the study
- •A disease that is in addition to the involvement of a nervous system with another serious illness, such as hemodynamic disorders, homeostasis disorders, diabetes, cardiovascular / pulmonary disease, etc.
- •Having a serious psychiatric illness or having a history of suicide
- •Treatment with cytotoxic drugs within a month before starting the study
- •The presence of any suspected malignancy mass
- •Serum creatinine more than 1.7
- •Rised liver enzyme tests more than three times
- •White blood cell count lower than 3000
- •Positive response to each of the serum tests of HTLV1,2 Ab, HIV1,2Ab, HBcAb, HBsAg,HCVAb
研究者
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