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临床试验/NCT07100444
NCT07100444已完成不适用

Spinal Metastasis as the First Presentation of Lung Malignancy: Clinical Characteristics and Postoperative Survival

Guangdong Provincial People's Hospital1 个研究点 分布在 1 个国家目标入组 139 人开始时间: 2018年1月1日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
139
试验地点
1
主要终点
Postoperative Overall Survival

研究概览

简要总结

The aim of this study is to compare the clinical features and postoperative survival outcomes between patients with spinal metastasis as the initial manifestation of malignancy and those with spinal metastasis occurring after an established diagnosis of malignancy.

详细描述

The aim of this study is to compare the clinical features and postoperative survival outcomes between patients with spinal metastasis as the initial manifestation of malignancy and those with spinal metastasis occurring after an established diagnosis of malignancy. By analyzing and contrasting these two groups, we seek to identify any distinctive characteristics, prognostic factors, and potential implications for early detection and treatment strategies in patients with malignant spinal metastases.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥ 18 years.
  • Pathologically or radiologically confirmed diagnosis of lung cancer with spinal metastasis.
  • Patients with spinal metastasis who underwent surgical intervention.
  • Adequate medical records and follow-up data available.

排除标准

  • Patients with spinal metastasis originating from non-lung primary tumors.
  • Patients who did not receive surgical treatment for spinal metastasis.
  • Incomplete clinical data or lost to follow-up.

结局指标

主要结局

Postoperative Overall Survival

时间窗: From the date of surgery until death or last follow-up, up to 5 years

Postoperative overall survival is defined as the time from the date of surgery for spinal metastasis to the date of death from any cause. Patients who are still alive at the last follow-up will be censored at that date. Survival status will be ascertained by clinical follow-up and/or review of medical records.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yu Zhang, PhD

Professor

Guangdong Provincial People's Hospital

研究点 (1)

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