Affiliated Hospital of Stomatology, School of Medicine, Zhejiang University
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Inflammatory markers analysis of the four groups
研究概览
简要总结
Analysis of inflammatory markers in periodontitis and patients with early and middle stage renal disease.
详细描述
A total of 200 population is recruited, individuals are divided into four groups according to a periodontal examination and a general physical examination: healthy individuals ,periodontitis, renal disease patients with healthy periodontium, and renal disease patients wth peridontitis. Fasting blood samples and gingival crevicular fluid are collected from all individuals, and inflammatory markers are analysed for the four groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 25 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •all participants were in general good health(except renal disease) and non-smoking
排除标准
- •less than 20 teeth in the dentin
- •hypertension
- •the presence of systemic disease (e.g., diabetes mellitus ,coronary heart disease, liver, or lung disease)
- •a history or the symptom of any other acute or chronic infections
- •systemic antibiotic treatment within previous 4 weeks
- •periodontal treatment within1 month
结局指标
主要结局
Inflammatory markers analysis of the four groups
时间窗: 3 months after sampling
Analysis of inflammatory biomarkers of blood and gingival crevicular fluid samples of the four groups
次要结局
未报告次要终点
研究者
Na Zhou
The stomatological hospital affiliated to medical college, Zhejiang University
Zhejiang University