Study of Arterial Recanalization of the Central Retinal Artery Occlusions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Dynamic retinal angiography data at 24 hours (+/- 24 hours)
研究概览
简要总结
Central retinal artery occlusions (CRAO) are the equivalent of an ischemic stroke (IS) at the retinal level. They share the same risk factors and common pathology. Their incidence is lower (8.5 / 100,000) and the functional prognosis is unfavorable in 80% of cases with visual acuity (VA) <1/10. The diagnosis of an CRAO is clinically based on the sudden occurrence of a decrease in deep visual acuity with fundamentally signs of reactive ischemia. There is no data on early retinal arterial recanalization after CRAO, nor on the relationship between early recanalization (spontaneous or post-thrombolysis) and visual prognosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Central Retinal Artery Occlusion ≤ 24 hours
排除标准
- •Retinal Dynamic angiography not performed within 48 hours of onset of symptoms
- •Occlusion of a branch of the central retinal artery
结局指标
主要结局
Dynamic retinal angiography data at 24 hours (+/- 24 hours)
时间窗: 24 hours (+/- 24 hours) following the beginning of symptoms
Proportion of patients with early arterial recanalization.The recanalization rate will be compared between thrombolysed patients and non-thrombolysed patients
次要结局
未报告次要终点