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临床试验/NCT03224533
NCT03224533已完成不适用

Association Between Walnut Consumption and Diabetes Risk in NHANES May be Gender Sex Specific

University of California, Los Angeles1 个研究点 分布在 1 个国家目标入组 34,121 人开始时间: 2015年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
34,121
试验地点
1
主要终点
Diabetes Outcome- Hemoglobin A1c

研究概览

简要总结

Multiple NHANES surveys were combined and weighted to evaluate relationships between walnut consumption and type 2 diabetes mellitus using various independent measures of diabetes status and risk. After risks were ascertained, interactions with gender were analyzed.

详细描述

Background. Dietary interventions and cohort studies of tree nuts lowering glucose levels for diabetes suggest a possible effect with walnuts. Objective. To examine the associations between walnut consumption and diabetes risk through data from the National Health and Nutrition Examination Survey (NHANES). Methods. NHANES survey data for 1999 through 2014 was pooled for adults with 24 hour recall dietary data. Risk of diabetes was based on self-report, medication use, fasting plasma glucose levels, and hemoglobin A1c (HbA1c) levels. Individuals were characterized as reporting consumption of walnuts, mixed 'nuts', or no nuts.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • NHANES data from 1999-2014 with food recalls and dietary food intake

排除标准

  • not having data on either day of the 24-hour food intake
  • individuals who consumed peanuts, but not other nuts on the day of recall, were excluded from the analysis

结局指标

主要结局

Diabetes Outcome- Hemoglobin A1c

时间窗: 1999-2014

Based on HbA1c levels

Diabetes Outcome- self report

时间窗: 1999-2014

Based on self-report as told by a doctor

Diabetes Outcome- Fasting Plasma Glucose

时间窗: 1999-2014

Based on FPG levels

Diabetes Outcome- Combined Definition

时间窗: 1999-2014

Based on both FPG and HbA1c levels

次要结局

  • Sex Interaction(1999-2014)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Lenore Arab, PhD

Principal Investigator

University of California, Los Angeles

研究点 (1)

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