Virtual Reality Exposure Therapy in Agoraphobic Participants
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 55
- 试验地点
- 1
- 主要终点
- Panic Disorder Severity Scale (PDSS); Mobility Inventory for Agoraphobia (MI); Behavioural Avoidance Test (BAT)
研究概览
简要总结
Virtual Reality Exposure Therapy (VRET) is an effective treatment for anxiety disorders, particularly for specific phobias as fear of heights and fear of flying (e.g. Powers & Emmelkamp, 2008). Recent technological advances (e.g. more realistic avatars) make research into the efficacy of VRET for participants with elevated agoraphobic symptoms desirable. Therefore, the aim of the present research proposal is to investigate the comparative efficacy of:
- enhanced VRET making use of the latest avatar technology with
- exposure in vivo in agoraphobic participants
- wait-list control.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A full diagnosis of panic disorder with agoraphobia according to the DSM-IV
- •Between the ages of 18-65 years
- •Sufficient fluency in Dutch to complete treatment and research protocol
排除标准
- •Presence of medical condition, assessed by self-report questionnaires at the intake (i.e., pregnancy, seizure disorder, pacemaker)
- •Current use of Beta-blockers
- •Current use of tranquilizers (Benzodiazepines)
- •Unstable psychotropic medication
- •Substance dependence
- •Psychosis
- •Depression with suicidal ideation
- •Posttraumatic Stress Disorder
- •Dementia or other severe cognitive impairment
- •Bipolar Disorder
- •Borderline Personality Disorder
- •Anti-social Personality Disorder
研究组 & 干预措施
VRET
Virtual Reality Exposure Therapy for agoraphobic participants
干预措施: Virtual Reality Exposure Therapy for agoraphobic participants (Behavioral)
Exposure in vivo
Standard exposure in vivo for panic disorder
干预措施: Standard exposure in vivo for agoraphobic participants (Behavioral)
Wait-list control
Wait-list control group. Participants from this arm are randomized to the two active conditions after 10 weeks of waiting.
结局指标
主要结局
Panic Disorder Severity Scale (PDSS); Mobility Inventory for Agoraphobia (MI); Behavioural Avoidance Test (BAT)
时间窗: Assessed at pre- and post-treatment and 6-12 months follow-up
次要结局
- Beck Anxiety Inventory (BAI); Anxiety Sensitivity Inventory (ASI); Beck Depression Inventory (BDI); Panic Disorder Severity Scale (PDSS); Agoraphobic Cognitions Questionnaire (ACQ); Bodily Sensations Questionnaire (BSQ); Panic Appraisal Inventory (PAI)(Process measures: are taken prior to treatment, after the fourth treatment session and at post-treatment. The PDSS and PAI will be administered every therapy session)
研究者
Paul M.G.Emmelkamp
Professor
VU University of Amsterdam