NCT05187273已完成不适用
Intraoperative Fluid Optimization Based on a Dynamic Elastance Protocol During Major Abdominal Surgery: a Randomised Control Trial
Fondazione Policlinico Universitario Agostino Gemelli IRCCS2 个研究点 分布在 1 个国家目标入组 46 人开始时间: 2021年2月25日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 46
- 试验地点
- 2
- 主要终点
- lactate levels
研究概览
简要总结
In this study investigators explore the effects of a dynamic elastance guided protocol compared to a stroke volume variation fluid therapy on lactate levels during major abdominal surgery. Hence investigators created two groups: in the intervention group fluids are given in fluid-responders (SVV > 13%) based on high value of dynamic elastance (ie. Eadyn > 0.9). In the standard group fluids are administered when SVV > 13%.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients enrolled for major abdominal surgery
排除标准
- •end-stage renal disease
- •severe heart dysfunction
- •heart rhythm alterations
结局指标
主要结局
lactate levels
时间窗: at the end of surgery
次要结局
未报告次要终点
研究者
RUSSO ANDREA
Principal Investigator
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
研究点 (2)
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