Comparative evaluation of clinical and radiographic outcomes of simultaneously placed implant in sinus augmented ridges with blood clot alone versus Platelet Rich Fibrin (PRF): A split mouth randomized clinical trial
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- simultaneous implant placement.
研究概览
简要总结
A dental implant is a biocompatible material placed into or onto the jawbone for prosthetic rehabilitation of a lost tooth. The vertical and horizontal bone volume in the posterior maxilla is important for implant placement. Ridge resorption and pneumatization of the maxillary sinus, as well as the poor quality of bone, may also make the implant rehabilitation of the posterior maxilla more challenging. Maxillary Sinus floor augmentation is the process in which the bone height and width is increased in order to stabilize the implant. Sinus floor can be augmented with or without the use of any grafts. PRF is considered a second-generation platelet concentrate because the natural concentrate is a product without any anticoagulants. If grafts are not used, the blood clot formed under the lifted maxillary sinus Schneiderian membrane appears to be critical importance in bone neoformation potential. The purpose of the study is to compare the vertical bone gain, bone density and probing depth of simultaneously placed implants in sinus augmented ridges with blood clot alone versus platelet rich fibrin (PRF).
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient aged more than 18 years.
- •Patient with severe atrophy of the posterior maxilla with 4-6 mm of residual bone height.
- •Patient with a need for implant therapy in the bilateral posterior maxillary region.
- •Patient coming under the category of ASA I.
- •Patient with pathology-free sinus.
- •Patient being without active periodontal diseases.
排除标准
- •Patient with systemic disease/condition that might interfere with implant placement.
- •Patient with active periodontal infection.
- •Patient with history of parafunctional habits.
- •Patient with habit of chronic smoking Patient with habit of chronic alcoholics.
- •Patient undergoing corticosteroid therapy, chemotherapy, radiotherapy.
- •Pregnant females.
- •Patient with lack of stable posterior occlusion.
- •Patient with a history of maxillary sinus pathologic features and/or surgery.
- •Patient coming under the category of ASA II, III, IV.
结局指标
主要结局
simultaneous implant placement.
时间窗: 6, 9 month
Researcher will come to know whether blood clot alone provides better bone gain when
时间窗: 6, 9 month
compared with Platelet Rich Fibrin (PRF) after maxillary sinus augmentation with
时间窗: 6, 9 month
次要结局
- Researcher will come to know whether blood clot alone provides better bone density when compared with Platelet Rich Fibrin (PRF) after maxillary sinus augmentation with(simultaneous implant placement.)