NCT04555369招募中不适用
Study on the Efficacy of Chemotherapy for Metastatic Colorectal Cancer Evaluated by Circulating Tumor DNA
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Response rate
研究概览
简要总结
The study is designed to evaluate the value of ctDNA in predicting the drug efficacy of chemotherapy for metastatic colorectal cancer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged ≥18 years with histologically or cytologically confirmed advanced colorectal adenocarcinoma Eastern Cooperative Oncology Group performance status of 0 to 2 life expectancy of ≥ 3 months at least one measurable metastatic lesion have adequate bone marrow, hepatic, and renal function
排除标准
- •patients with previous chronic inflammatory bowel disease, chronic diarrhea or recurrent bowel obstruction patients with symptomatic brain metastases active clinical severe infection
结局指标
主要结局
Response rate
时间窗: 2 months
the response rate predicted by ct-DNA
次要结局
- Overall survival(2 months)
- Progression free survival(2 months)
研究者
Weijian Guo
MD,PhD, Fudan University Shanghai Cancer Center
Fudan University
研究点 (1)
Loading locations...
相似试验
进行中（未招募）
3 期
Cancer Stem Cell Assay Directed Chemotherapy in Recurrent Platinum Resistant Ovarian CancerRecurrent Ovarian CarcinomaPlatinum-resistant Ovarian CancerNCT03949283Cordgenics, LLC150
终止
不适用
Combination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal CancerMetastatic Colorectal CancerNCT01280643Fox Chase Cancer Center3
已完成
不适用
Evaluation of effect of chemotherapy for depiction of metastatic liver tumor on gadoxetate disodium enhanced MRIJPRN-UMIN000005401Hiroshima University20
Unknown
2 期
Study Assessing the Effects of Chemotherapy in Advanced Esophagogastric AdenocarcinomaEsophageal NeoplasmsStomach NeoplasmsNCT02177552Rigshospitalet, Denmark98
已完成
不适用
Chemotherapeutic Agents in Brain/BreastMetastatic CancerBreast CancerNCT00795678Case Comprehensive Cancer Center10