NL-OMON49754已完成不适用
Trained immunity in bone marrow progenitors as driver of atherosclerosis in obesity. - TRIM in obesity
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •-Participant in 300OB cohort, so all have a BMI> 27 and age >18 years
- •-Written informed consent
- •-4 weeks prior to inclusion stop cholesterol lowering drugs such as: statins
排除标准
- •-Inability to personally provide written informed consent (e.g. for linguistic
- •or mental reasons)
- •-Documented bleeding diathesis or thrombocytopenia <50 *10e9/L
- •-History of haematological malignant disease
- •-Current treatment for maligancy
- •-Acute or chronic infections at the time of participation
- •-Medical history of any disease associated with immune deficiency (either
- •congenital or acquired, including chemotherapy, chronic steroid use, organ
- •transplant)
- •-Clinically significant infections within 1 months prior to study entry
- •(defined as fever >38.5)
- •-Previous vaccination within 1 months prior to study entry
- •-Chronic use of anti-inflammatory drugs such as NSAIDs (acetylsalicylic acid
- •<100 mg/day excluded)
研究者
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