Levels of Visfatin/NAMPT in Human Milk.VISFAMILK
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Visfatin levels
研究概览
简要总结
Visfatin, released in maternal milk at different concentrations related to the maternal conditions, could act as a biomarker with a prognostic/predictive value to determine different newborn clinical conditions, particularly the weight loss of the neonate.
详细描述
The aim of the study is to analyse a retrospective cohort of well characterized mothers in their post-partum period, and to measure Visfatin levels through collection of maternal milk samples. They will be collected in three different moments after the birth (48 hours, 7 days and 30 days) and Visfatin levels will be analysed through an ELISA kit Adipogen. In parallel, the levels of Visfatin will be evaluated in the maternal plasma/serum collected after 1-2 days postpartum.
Lastly, correlations between Visfatin levels and biological/clinical features of mothers and newborns will be explored.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Healthy male and female infants born after 37 weeks' gestation who do not have conditions related to congenital abnormalities
- •Maternal hospitalization
- •Acquisition of the informed consent form signed by the patient
排除标准
- •Refusal of the patient to participate in the study
- •Presence of hypogalactia or agalactia in the patient
结局指标
主要结局
Visfatin levels
时间窗: 1-2 days post-partum
Visfatin levels in maternal plasma/serum
次要结局
- values of Visfatin(6 months)
研究者
Paolo Manzoni Study Group
Principal Investigator, Head of Department of Maternal, Neonatal and Infant Medicine, Associate Professor
Paolo Manzoni