Investigation of the Effects of Different Exercise Approaches on Exercise Capacity, Muscle Parameters and Quality of Life in Chronic Obstructive Pulmonary Disease Patients
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 44
- 试验地点
- 2
- 主要终点
- Maximal exercise capacity
研究概览
简要总结
The beneficial effects of exercise training in individuals with chronic obstructive pulmonary disease (COPD) are well known. Standard exercise training includes structured aerobic exercise training and resistance exercise training programs applied to upper and lower extremity muscle groups. No study has been found in the literature that includes a trunk stabilization training program that includes muscles that provide whole body stabilization in COPD patients.
详细描述
The investigators aimed to determine the effects of an aerobic exercise training program, resistance exercise training, and an additional trunk stabilization training program in individuals with COPD.
Individuals diagnosed with COPD between the ages of 40-80 who applied to Ankara Etlik City Hospital Chest Diseases Polyclinic will be included in the study. Data collection tools and exercise training programs will be made by the same researchers. A total of 44 COPD patients, 22 in each group, will be included in the study.
COPD individuals who agree to participate in the study will be randomised electronically using a randomisation program and participants will be divided into two groups.
Group 1: Aerobic exercise training and resistance exercise training and trunk stabilisation strength training Group 2: Aerobic exercise training, resistance exercise training and respiratory exercise training
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Having a diagnosis of COPD
- •Being between the ages of 40-80
- •Being clinically stable (not having had an exacerbation in the last month)
- •Being able to cooperate with the tests
- •Not participating in any exercise training studies
- •Being willing to participate in the study
排除标准
- •Having other lung or lung involvement diseases other than COPD
- •Having uncontrolled hypertension, arrhythmia and a history of myocardial infarction in the last month, unstable angina, advanced heart failure and other cardiac instability conditions
- •Being hemodynamically unstable
- •Being on noninvasive mechanical ventilation (NIMV) and long-term oxygen therapy (LTOT)
- •Having a history of neuromuscular disease, scoliosis, chest wall surgery
- •Being pregnant and having a malignancy
- •Having an orthopedic or surgical problem that would prevent participation in tests and exercise training
- •Not being willing to participate in the study
结局指标
主要结局
Maximal exercise capacity
时间窗: 8 weeks
Maximal exercise capacity will be assessed by cardiopulmonary exercise testing (CPET) using a workload protocol of increasing intensity. Monitoring will be provided with 12-lead electrocardiography at rest, during testing and recovery. During CPET, data will be recorded with the "breathe-by-breathe" method through a face mask and a gas analyzer.
次要结局
- Forced expiratory volume (FEV1)(8 weeks)
- Forced Vital Capacity (FVC)(8 weeks)
- Respiratory muscle strength(8 weeks)
- COPD Assessment Questionnaire(8 weeks)
- Muscle activity(8 weeks)
- Muscle Thickness(8 weeks)
- Timed up and go test(8 weeks)
- Functional reach test(8 weeks)
- St George Health Questionnaire(8 weeks)
- Hospital Anxiety and Depression Scale(8 weeks)
- Six Minute Walk Test (6MWT)(8 weeks)
研究者
Elif Cansu Özkılıçaslan
Physiotherapist, M.Sc
Hacettepe University