Effectiveness of Tai Chi Training to Alleviate Metabolic Syndrome in Abdominal Obese Older Adults: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 543
- 试验地点
- 4
- 主要终点
- Waist circumference
研究概览
简要总结
Metabolic syndrome (MetS) is a serious public health problem in Hong Kong and worldwide. Older adults, the age group with the highest prevalence of MetS, may prefer specific exercise modalities that are suitable for their regular participation to manage MetS. This project aims to evaluate the effectiveness of Tai Chi, a very suitable exercise for older adults, to alleviate MetS in older population
详细描述
PURPOSE/OBJECTIVE: Metabolic syndrome (MetS) is a serious public health problem in Hong Kong and worldwide. Older adults, the age by specific exercise modalities that are suitable for regular participation. This project aims to evaluate the effectiveness of Tai Chi to alleviate MetS in older population.
DESIGN & METHODS: This study is a three-arm assesscer blinded randomized controlled trial. Older adults aged 50 years or above with abdominal obesity will be randomly assigned to passive control, active control and Tai Chi groups. Subjects assigned to Tai Chi and active control groups will receive a 12-week intervention of Tai Chi and generic fitness, respectively. No intervention will be given to the passive control group. Outcome measures including waist circumference, blood pressure, blood glucose, triglyceride and high density lipoprotein-cholesterol will be assessed at baseline, post-intervention and follow-up (6 months after the end of intervention) assessments in all groups.
HYPOTHESES: We hypothesize that: 1) improvements of waist circumference and other indicators of MetS are found in Tai Chi group but not in passive control group and 2) improvements of waist circumference and other indicators of MetS are more profound in Tai Chi group than active control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ethnic Chinese
- •Abdominal Obese: Meeting the defined criteria of International Diabetes Federation (IDF) and National Cholesterol Education Program (NCEP) for abdominal obesity using Asian-specific cut off (waist circumference ≥ 90 cm for male; ≥ 80 cm for female)
排除标准
- •Regularly practice moderate-intensity exercise or tai chi (>3 times a week of >30-min/ session)
- •Serious medical and somatic condition that prevent participation in generic fitness/Tai Chi exercise
- •Serious chronic diseases known to affect mobility (eg. Neurological diseases, musculoskeletal disorder and autoimmune diseases)
- •Under treatment for serious chronic diseases (eg. Cancer treatment)
结局指标
主要结局
Waist circumference
时间窗: 6 months after the completion of intervention
Waist circumference will be measured midway between the lowest rib and the superior border of the iliac crest using an inelastic measuring tape on the bare skin to the nearest 0.1 cm. Measurement will be performed at the end of normal expiration.
次要结局
- Remission of central obesity(Immediately after completion of the 12-week intervention and 6 months after the completion of intervention)
- Blood triglyceride(Immediately after completion of the 12-week intervention and 6 months after the completion of intervention)
- High density lipoprotein-cholesterol(Immediately after completion of the 12-week intervention and 6 months after the completion of intervention)
- Fasting blood glucose(Immediately after completion of the 12-week intervention and 6 months after the completion of intervention)
- Systolic blood pressure(Immediately after completion of the 12-week intervention and 6 months after the completion of intervention)
- Diastolic blood pressure(Immediately after completion of the 12-week intervention and 6 months after the completion of intervention)
- Bodyweight(Immediately after completion of the 12-week intervention and 6 months after the completion of intervention)
- Body mass index(Immediately after completion of the 12-week intervention and 6 months after the completion of intervention)
研究者
Angus Yu
Research Assistant
The Hong Kong Polytechnic University