Associations of Nighttime Light Exposure During Pregnancy With Neonatal Jaundice：a Multi-centre Prospective Study in China
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 2,977
- 试验地点
- 1
- 主要终点
- Hour-specific Transcutaneous Bilirubin Level
研究概览
简要总结
Make a neonatal jaundiced nomogram on Chinese jaundice data by joinning the major neonate centers all around China.
详细描述
This was a multi-centre prospective study. All infants included were born in 8 hospitals in the southern, eastern, northern, western and central regions of mainland China in 2019. A total of 20839 transcutaneous bilirubin(TCB) measurements were performed with 2977 neonates at designated time points. The mean NTL exposure during pregnancy was respectively calculated based on each participant's residential address over the study course. The primary outcome was whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life. The effect of maternal nocturnal light exposure on neonate jaundice analyzed with lasso regression and random forest machine learning methods.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 1 Day 至 7 Days（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •gestational age more than 35 weeks(≥35) -
排除标准
- •all kinds of congenital diseases, infants with pathologic jaundice
结局指标
主要结局
Hour-specific Transcutaneous Bilirubin Level
时间窗: 1 year
make neonatal jaundiced nomogram base on the hour-specific transcutaneous bilirubin data
whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life
时间窗: 2019
whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life
次要结局
未报告次要终点
研究者
yang jie
Director of neonatology of GuangdongWCH
Guangdong Women and Children Hospital