A RANDOMISED COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF ASHWAGANDHADYA GHRITA PANA AND NASYA ALONG WITH RASNAPANCHAK KWATHA AND GUGGULU VATI IN MANAGEMENT OF CERVICAL SPONDYLOSIS (GREEVA SANDHIGATAVATA)
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- The primary outcome of the study will be the change in Neck Disability Index Score
研究概览
简要总结
The study titled "A Randomized Comparative Clinical Study to Evaluate the Efficacy of Ashwagandhadya Ghrita Pana and Nasya along with Rasnapanchak Kwatha and Guggulu Vati in Cervical Spondylosis (Greeva Sandhigatavata)" is a postgraduate research project in Ayurveda.BackgroundCervical Spondylosis is a degenerative condition affecting the cervical spine, leading to neck pain, stiffness, and neurological complications. The study correlates this condition with Greeva Sandhigata Vata in Ayurveda and aims to explore the effectiveness of Ayurvedic treatments for pain relief and functional improvement.
I. Null Hypothesis [Ho]- There is no difference between the efficacy of Ashwagandhadya ghritapana and nasya along with Rasnapanchak kwatha and Guggulu Vati in Cervical Spondylosis
II. Alternative Hypothesis [HA]- There is difference between the efficacy of Ashwagandhadya ghritapana and nasya along with Rasnapanchak kwatha and Guggulu Vati in Cervical Spondylosis
Study Design
- Type: Randomized, Comparative Clinical Trial
- Participants: 40 patients (30–70 years) diagnosed with Cervical Spondylosis
- Groups:
- Group A: Ashwagandhadya Ghrita Pana, Guggulu Vati, and Rasnapanchak Kwatha
- Group B: Ashwagandhadya Ghrita Nasya, Guggulu Vati, and Rasnapanchak Kwatha
- Duration: 28 days with follow-up after 1 month
Treatment & Methodology
- Ashwagandhadya Ghrita is used for its Vata-balancing and Brimhana properties.
- Guggulu Vati supports joint health and reduces inflammation.
- Rasnapanchak Kwatha relieves pain, strengthens muscles, and improves digestion.
- Efficacy is measured using the Neck Disability Index (NDI), pain scales, and radiological findings.
Outcome & SignificanceThe study aims to provide scientific evidence on Ayurvedic treatments as an alternative to conventional therapies, reducing dependency on NSAIDs and steroids while improving patients’ quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of either gender having age between 30-70 years
- •Patients with clinical signs and symptoms of Greeva sandhigata vata (Cervical Spondylosis)
- •Patients having a radiological finding of Cervical Spondylosis
- •Patients fit for Nasya karma and Snehapana.
排除标准
- •Recent cervical, spinal, or shoulder trauma or surgery or any implantation in these sites
- •History of Cervical Spondylotic Myelopathy, Cervical Rib, severe Cervical Radiculopathy
- •Patients having systemic illness such as Ankylosing spondylitis, diffuse idiopathic skeletal hyperostosis, inflammatory arthritis
- •Patients having suspected TB or HIV infection, vascular insufficiency or malignancy
- •Pregnant or lactating women
- •Patients having known allergy to any of the trial drug.
结局指标
主要结局
The primary outcome of the study will be the change in Neck Disability Index Score
时间窗: At baseline and after four weeks
次要结局
- Secondary outcomes will include changes in scoring of subjective parameters assessing pain, neck stiffness and active neck movements (From baseline to the end of the treatment period)(After four weeks)
研究者
RACHNA SHARMA
NATIONAL INSTITUTE OF AYURVEDA, JAIPUR