Observational Study on the Safety of Accelerated Rule-out Protocols in Patients Admitted With Chest Pain to a Crowded CPU
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3,567
- 试验地点
- 1
- 主要终点
- All-cause death
研究概览
简要总结
The aim of this observational study registry is to assess the safety of a Non-ST-elevation myocardial infarction (STEMI) rapid rule-out strategy as proposed by European Guidelines in patients presenting with suspected acute coronary syndrome to the emergency department.
详细描述
Design: mono-center observational study in a University chest pain unit
Duration: 12 months recruitment period starting June 2016 with end of recruitment July 2017. In the first 6 months assessment of situation, January 2017 introduction of fast protocols, i.e. 0/1 h as standard, observation of trend changes, utilization rates, safety from January 1st until July 2017. Another 90 days follow-up after last patient in.
Background: Several rule-out protocols recommended by 2015 European Society of Cardiology (ESC) guidelines, evidence supported by prospectively validated studies. However, no real life experience with ultilization rates and safety.
Particularly overcrowded emergency departments (EDs) or CPUs are likely to benefit most from fast rule-out protocols in order to discharge a substantial proportion of low risk patients.
Study group: consecutive patients presenting to CPU with suspected acute coronary syndrome (ACS) based on chest pain or chest pain equivalent symptoms
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •eligible to consent
- •>18 years
排除标准
- •NSTEMI rule-in
- •hs-TnT in observational zone
- •chronic hemodialysis
- •no consent
- •atrial tachyarrhythmias with chest pain or equivalent
结局指标
主要结局
All-cause death
时间窗: 30 days and 3 months
Survival free of all-cause death
次要结局
- Rehospitalization for Acute Coronary Syndrome(30 days and 3 months)
- Acute Myocardial Infarction(30 days and 3 months)
- Rehospitalization for nonelective percutaneous coronary intervention(30 days and 3 months)
研究者
Dr. Moritz Biener
Principal Investigator
University Hospital Heidelberg