Efficacy of Flomax to Improve Stone Passage Following Shock Wave Lithotripsy
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Time to Passage of Stone Fragments
研究概览
简要总结
The majority of kidney stones are treated with shock wave lithotripsy (SWL). We are examining if the medication Flomax will result in improved stone passage rates following SWL.
详细描述
Placebo blinded study examining the effects of Flomax on stone passage rates following SWL.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients 18 years old and above with urolithiasis scheduled for shock wave lithotripsy.
排除标准
- •Contraindications to Flomax
- •Patients with renal impairment (serum creatinine above 2.0)
- •Patients with hepatic impairment (liver enzymes 2.5 times the upper limit of normal)
- •Use of other oral alpha blockers
研究组 & 干预措施
Flomax
Patients on this arm will be given 0.4mg of Flomax to be taken for one month following their shock wave lithotripsy procedure.
干预措施: Flomax (Drug)
Sugar pill
Patients on this arm will be given a sugar pill to be taken for one month following their shock wave lithotripsy procedure.
干预措施: Sugar pill (Drug)
结局指标
主要结局
Time to Passage of Stone Fragments
时间窗: 2 weeks and 3 months
Time to passage of stone fragments following shock wave lithotripsy as documented by patient diaries and follow-up radiographic imaging.
次要结局
- Medical Evaluation(2 weeks and 3 months)
研究者
Kenneth Ogan, MD
Associate Professor
Emory University