Efficacy of the Memory Motivation (MEMO) Web Application for Cognitive and Behavioral Training in Patients With Neurocognitive Disorders
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 49
- 试验地点
- 2
- 主要终点
- Change is being assessed with the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)
研究概览
简要总结
Memory, attentional, and behavioural symptoms are the clinical hallmarks of Neurocognitive disorders (NCD) such as Alzheimer's disease and related disorders. The World Health Organisation (WHO) guidelines for risk reduction of cognitive decline and dementia indicate that Cognitive training may be offered to older adults with normal cognition and with mild cognitive impairment to reduce the risk of cognitive decline and/or dementia. The use of Information and Communication Technologies (ICT) in the health domain is progressively expanding. The Alzheimer Innovation Association have developed MeMo (Memory Motivation) a free web application that can be used at home by patients.
The objective of the present study was to assess the effectiveness of employing the MeMo platform on cognitive performance in patients suffering from NCD.
详细描述
The objective of this study is to evaluate the effectiveness of the MeMo cognitive training exercise platform in patients suffering from neurocognitive disorders. These exercises ,have been developed by the association Innovation Alzheimer and the CoBTeK research team, located with the Nice memory Center at the Institut Claude Pompidou. MeMo can be used freely at home by patients. More specifically, it is a randomized controlled study that aims to compare the evolution of activities cognition and behavior between patients not using these exercises, and patients using these exercises for 12 weeks, 4 sessions per week.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
盲法说明
Randomization for the allocation of the patient in each group
入排标准
- 年龄范围
- 60 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Outpatient consulting the Memory center
- •older than 60 years old
- •Mini Mental State examination score (MMSE) between 16 and 28 / 30
- •met the DSM 5 diagnoses of mild neurocognitive disorders (mild NCD) or major neurocognitive disorders (Major NCD).
排除标准
- •Patients not able to read and write French
- •presence of a hearing or major visual impairment
- •a history of premorbid mental retardation
- •had already used the MeMo application
- •were presently involved in structured memory training activities.
研究组 & 干预措施
MeMo group
MeMo group: experimental: regular use at home of the Memo web application In the Memo group patients were instructed on how to use the application, and allowed to train for 12 weeks. It was also explained that this training needed to be done regularly on a basis of 4 sessions of 30 minutes each per week.
干预措施: MeMo web application (Device)
Control group
Regular follow up at the memory center without cognitive training
干预措施: Control group (Other)
结局指标
主要结局
Change is being assessed with the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)
时间窗: Base line, Week 12
To score the IQCODE, add up the score for each question and divide by the number of questions. For the long IQCODE, divide by 26.
次要结局
- Change in attention is is being assessed with the DSST(Base line, Week 12)
- Change in frontal functioning is being assessed with the FAB(Base line, Week 12)
- IA-C(Base line, Week 12)
- Change in behavior is being assessed with the NPI(Base line, Week 12)
研究者
Philippe robert, MD, PhD
Professor of Psychiatry
Innovation Alzheimer