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临床试验/NCT04367220
NCT04367220招募中不适用

Cardiovascular Imaging Registry of Canada

University of Calgary4 个研究点 分布在 1 个国家目标入组 45,000 人开始时间: 2014年8月最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
45,000
试验地点
4
主要终点
Malignant arrhythmic events

研究概览

简要总结

A multi-site, multi-modality prospective observational clinical outcomes study focussed on the development of phenotype-dirven risk prediction modelling in patients with known or suspected cardiovascular disease.

详细描述

The Cardiovascular Imaging Registry of Canada (CIROC) was conceived to provide a common standardized architecture for the collection of clinically reported imaging biomarkers, demographic information, resource utilization and clinical outcomes among patients referred to non-invasive cardiac imaging. The Registry was designed to assess the feasibility of implementing personalized care strategies through automated high quality data collection and patient engagement.

The CIROC Registry was launched with inaugural focus on Cardiac MRI base phenotyping, however has evolved to encompass cardiac CTA and echocardiography. Clinically referred patients are engaged by automated, tablet-based tools to collect informed consent and deploy standardized patient health assessments. Standardized reporting of disease features are captured using bespoke reporting tools. All patients are prospectively followed for a period of 10-years using linkage to administrative health data, inclusive of ICD-coded events, laboratory test results, ECG and vital statistics.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients referred for hospital-based cardiac imaging services

排除标准

  • Failure or provide informed consent

结局指标

主要结局

Malignant arrhythmic events

时间窗: 2024

Composite of sudden cardiac death or appropriate ICD shock

Heart failure events

时间窗: 2024

Composite of heart failure admission, death or need for transplantation / LVAD

Atrial arrhythmic events

时间窗: 2024

Occurrence of atrial fibrillation / atrial flutter (documented by 12-lead ECG or Holter monitor)

Major adverse cardiovascular outcomes (MACE)

时间窗: 2024

Composite of all-cause death, heart failure admission, myocardial infarction, heart transplantation or LVAD, Stroke or TIA

All-cause mortality

时间窗: 2024

Death based on Vital Statistics Alberta and In-hospital coded death

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

James White

MD, FRCP(C) Director - Stephenson Cardiac Imaging Centre

University of Calgary

研究点 (4)

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