Cardiovascular Imaging Registry of Canada
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 45,000
- 试验地点
- 4
- 主要终点
- Malignant arrhythmic events
研究概览
简要总结
A multi-site, multi-modality prospective observational clinical outcomes study focussed on the development of phenotype-dirven risk prediction modelling in patients with known or suspected cardiovascular disease.
详细描述
The Cardiovascular Imaging Registry of Canada (CIROC) was conceived to provide a common standardized architecture for the collection of clinically reported imaging biomarkers, demographic information, resource utilization and clinical outcomes among patients referred to non-invasive cardiac imaging. The Registry was designed to assess the feasibility of implementing personalized care strategies through automated high quality data collection and patient engagement.
The CIROC Registry was launched with inaugural focus on Cardiac MRI base phenotyping, however has evolved to encompass cardiac CTA and echocardiography. Clinically referred patients are engaged by automated, tablet-based tools to collect informed consent and deploy standardized patient health assessments. Standardized reporting of disease features are captured using bespoke reporting tools. All patients are prospectively followed for a period of 10-years using linkage to administrative health data, inclusive of ICD-coded events, laboratory test results, ECG and vital statistics.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients referred for hospital-based cardiac imaging services
排除标准
- •Failure or provide informed consent
结局指标
主要结局
Malignant arrhythmic events
时间窗: 2024
Composite of sudden cardiac death or appropriate ICD shock
Heart failure events
时间窗: 2024
Composite of heart failure admission, death or need for transplantation / LVAD
Atrial arrhythmic events
时间窗: 2024
Occurrence of atrial fibrillation / atrial flutter (documented by 12-lead ECG or Holter monitor)
Major adverse cardiovascular outcomes (MACE)
时间窗: 2024
Composite of all-cause death, heart failure admission, myocardial infarction, heart transplantation or LVAD, Stroke or TIA
All-cause mortality
时间窗: 2024
Death based on Vital Statistics Alberta and In-hospital coded death
次要结局
未报告次要终点
研究者
James White
MD, FRCP(C) Director - Stephenson Cardiac Imaging Centre
University of Calgary
