NCT07220655招募中不适用
Cognition and Ultrasound
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Deep Brain Targets Reached
研究概览
简要总结
Our primary goal is to investigate the role of Low-Intensity Focused Ultrasound (LIFU) neuromodulation on deep brain targets, and its potential to improve cognition
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years of age or older
- •Speak English (as assessed by their ability to read/answer survey questions)
- •May be required to score in the appropriate range on self-report measures
排除标准
- •They have a neurological disorder which may impact their fMRI scan or cause their reaction to LIFU to differ from that of healthy adults.
- •They take any psychoactive medication.
- •They are unable to undergo fMRI scanning due to a contraindication such as claustrophobia, unremovable piercings, pregnancy, the presence of medical devices such as pacemakers, or a movement or sleep disorder.
- •Are pregnant, or may have reason to believe that they are pregnant.
- •They have a diagnosis of a psychiatric condition other than depression or anxiety
结局指标
主要结局
Deep Brain Targets Reached
时间窗: Hour 1
MRI-based readouts testing whether LIFU neuromodulation can successfully engage targets in deep brain
Multi-Source Interference Test (MSIT) Performance
时间窗: Hour 1
Behavioral readouts of successful LIFU neuromodulation of our target regions
28/Posit Science Performance
时间窗: Hour 1
Behavioral readouts of successful LIFU neuromodulation of our target regions
次要结局
未报告次要终点
研究者
研究点 (2)
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