Postoperative Events in Patients With and Without Retained Nuclear Fragments in the Anterior Vitreous After Routine Phacoemulsification
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Macular edema
研究概览
简要总结
The purpose of this study is to investigate postoperative events in patients noted to have retained nuclear fragments in the anterior vitreous during routine phacoemulsification and in those who did not.
详细描述
In this study, we investigate whether presence of retained nuclear fragments in the anterior vitreous noted during uncomplicated cataract surgery is associated with higher incidence of postoperative adverse events. We will be assessing events including cystoid macular edema, iritis, elevated intraocular pressure, and retinal detachment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Routine cataract surgery with phacoemulsification
排除标准
- •Pre-existing macular edema
- •Active uveitis
- •Intraocular exclusion surgeries
- •Significant ocular trauma
- •Evidence of phacodonesis or zonular weakness .
结局指标
主要结局
Macular edema
时间窗: 1 month postoperatively
Proportion of eyes with clinical macular edema and subclinical macular edemas measured by OCT at 1 month postoperatively
次要结局
- Intraocular inflammation(1 month postoperativley)
- Elevated intraocular pressure(1 month postoperatively)
- Macular Edema(3 months postoperatively)
- Intraocular Inflammation(3 months)
- Elevated Intraocular Pressure(1 week postoperatively)
研究者
David Ritterband
MD
Ophthalmic Consultants, Corneal and Refractive Surgery Associates, PC