agasaki Investigation of Candesartan Effects -the Comparison Between an Increased Candesartan and the additional Diuretics- - NICE-C

Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences0 个研究点目标入组 100 人开始时间: 2010年8月7日最近更新: 2023年10月17日

适应症

试验速览

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•Exclusion criteria comprised any of the following: (1)Patients under treatments with antihypertensive agents except diuretics who will not continue to take 8mg/day of candesartan for at least 3 months. (2)Administration of diuretics or of agents influencing rennin-angiotensin-aldosterone system except for candesartan. (3)Concomitant medications which are expected to be frequently changed. (4)Under treatment of insulin for diabetes. (5)Severe renal dysfunction (eGFR<30 mL/min/1.73m2) (6)Heart failure (NYHA classification III or IV) (7)Malignant hypertension and secondary hypertension. (8)Myocardial infarction, stroke, and revascularization therapies of coronary arteries and/or peripheral arteries within 6 months prior to the registration of this study. (9)Pregnant female (10)Allergic disorder which is problem in the clinical setting. Hypersensitivity or contraindication to candesartan or hydrochlorothiazide. (11)Patients who are judged by doctors as inappropriate patients for the entries of this study

发起方

Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences