Comparison Between Bandage Contact Lens and Pressure Patching for The Erosion Area and Pain Scale in Corneal Erosion Patients
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 32
- 试验地点
- 2
- 主要终点
- Size of corneal erosion area
研究概览
简要总结
This research aims to compare between bandage contact lens and pressure patching in reducing size of erosion area and pain scale in corneal erosion patients as well as its complications.
详细描述
This is a randomized open-label clinical trial in patients with mechanical corneal erosion. Subjects were selected to use bandage contact lens (Senofilcon A) or pressure patching. All subjects received combination of Polymyxin B, Neomycin, and Gramicidin eye drops and 0,5% Tropicamide eye drops. Evaluation was done 24 hours after treatment
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 17 Years 至 55 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged 17-55 years
- •onset of corneal erosion < 48 hours
- •corneal erosion due to mechanical injury
- •extensive corneal erosion > 3 mm2
排除标准
- •bilateral corneal erosion
- •corneal erosion due to chemical or thermal injury
- •history of systemic analgesic use within 1 week prior to the examination or topical analgesics within 1 hour before the examination
- •history of systemic or topical antibiotics within 1 week prior to the examination
- •other abnormalities due to trauma
- •palpebral or eyelashes position abnormalities
- •anterior segment infections
- •tear break-up time < 7 seconds in the contra lateral eye
结局指标
主要结局
Size of corneal erosion area
时间窗: 24 hour
Corneal erosion area is the multiplication of the long and short axis of corneal erosion, as measured using a caliper, with the help of fluorescein and cobalt blue slit lamp beam
次要结局
- Pain scale(24 hour)
研究者
Ni Nyoman Triharpini
Resident in Depatment of Ophthalmology Faculty of Medicine
Udayana University