Evaluation of the Use of Arterial Pulse Waveform Contour Analysis for Goal Directed Therapy in Patients Undergoing Major Spine Surgery
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 5
- 试验地点
- 1
- 主要终点
- Evaluation of the Use of Arterial Pulse Waveform Contour Analysis for Goal Directed Therapy in Patients Undergoing Major Spine Surgery
研究概览
简要总结
This study evaluates whether using information from a special arterial blood pressure monitor to guide how much fluid is given during surgery changes how long a patient stays in the hospital after the surgery. There is scientific evidence from using similar information from different devices that this technique might allow us to do a better job giving fluids during surgery and that this may be associated with a shorter hospital stay after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients scheduled for major spine surgery at LLUMC University Hospital will be eligible for participation in this study
排除标准
- •age under 18yr,
- •coagulopathy, significant renal or hepatic dysfunction (creatinine or liver enzymes > 50% above normal values),
- •congestive heart failure,
- •cardiac arrhythmias producing irregular rhythms, and patient refusal.
研究组 & 干预措施
Standard fluid management
Standard intraoperative fluid management as determined by usual monitoring and decision making applied by anesthesiology team
Vigileo model number MHM1
Pulse contour waveform analysis derived stroke volume variation will be used to guide intraoperative fluid administration. Additional fluid boluses will be given to the patient when SVV>12%.
干预措施: goal directed therapy (Other)
结局指标
主要结局
Evaluation of the Use of Arterial Pulse Waveform Contour Analysis for Goal Directed Therapy in Patients Undergoing Major Spine Surgery
时间窗: From end of surgey to approximately 1 week
time in days from the end of surgery to hospital discharge
次要结局
- Evaluation of the Use of Arterial Pulse Waveform Contour Analysis for Goal Directed Therapy in Patients Undergoing Major Spine Surgery(from the end of surgery to approximately 1 month)
研究者
Richard Applegate
MD
Loma Linda University