Hepatectomy With or Without the Thoraco-abdominal Approach: Impact on Perioperative Outcome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 744
- 主要终点
- Short-term outcome: Occurrence of postoperative complications or death after surgery
研究概览
简要总结
The performance of hepatectomy for liver tumors using the thoraco-abdominal approach (TAA) versus the abdominal approach (AA) is still debated.
The aim of the study is the analysis of the perioperative outcome of patients operated with or without the TAA for liver tumors.
详细描述
The prospectively maintained database was queried. A 1:1 propensity score-matched analysis was applied. Among 744 patients, 246 undergoing hepatectomy with TAA and 246 undergoing hepatectomy with AA were compared. These patients were matched for baseline characteristics, underlying liver disease, comorbidity, tumor features, and extent of the resection. The rates of morbidity and mortality were the study endpoints.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •First liver surgery;
- •Any type of malignant liver tumor, including hepatocellular carcinoma on cirrhosis.
排除标准
- •Previous history of liver surgery;
- •Any type of benign liver tumor;
- •Incomplete clinical, surgical, pathological or postoperative data;
- •Patients treated with radiofrequency ablation alone or in combination with surgery were also excluded.
结局指标
主要结局
Short-term outcome: Occurrence of postoperative complications or death after surgery
时间窗: Within 90-days after the operation
Occurrence of postoperative complications or death after surgery
次要结局
未报告次要终点
研究者
Prof. Guido Torzilli
Director of the Department of Hepatobiliary Surgery
University of Milan