Retrospective Tube Feeding Tolerance in Adults With Intolerance After Switch to a Peptide-based Formula
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Feeding tolerance - vomiting
研究概览
简要总结
A retrospective chart review to assess feeding tolerance in adults who had been switched from an intact protein formula to a peptide-based formula due to feeding intolerance in a complex continuing care facility.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •> 18 years of age on admission to facility
- •Prescribed enteral nutrition with the goal to provide at least 90% of estimated daily calorie and protein requirements for ≥ 2 weeks prior to switch
- •Received enteral nutrition with an intact protein formula for a minimum of three days prior to a switch to a peptide-based formula
- •Have documentation of intolerance to an intact protein formula, followed by a switch in formula received to a peptide-based formula
- •Receiving a peptide-based formula formula for ≥ 2 weeks
- •Have documentation of an assessment of feeding tolerance following the switch
- •Formulas received must be indicated for use in adults.
排除标准
- •Abdominal surgery (within past 30 days prior to switch)
- •Having any infection, including upper respiratory, viral, gastroenteritis,wound infections, c difficile, at time of switch
- •Having documented cow's milk protein allergy at time of switch
- •Medical records lacking information on rationale for switch to a peptide-based formula and/or response to change (positive, neutral or negative).
结局指标
主要结局
Feeding tolerance - vomiting
时间窗: Up to 30 days after formula switch
no change, tolerance improved, tolerance worsened
Tube feeding interruptions
时间窗: Up to 30 days after formula switch
Number of tube feeding interruptions
Feeding tolerance - Gastric residuals
时间窗: Up to 30 days after formula switch
no change, tolerance improved, tolerance worsened
Feeding tolerance - stool consistency issues
时间窗: Up to 30 days after formula switch
too hard, too loose
Feeding tolerance - abdominal distension/gas
时间窗: Up to 30 days after formula switch
no change, tolerance improved, tolerance worsened
Volume of formula consumed in a day vs. goal
时间窗: Up to 30 days after formula switch
documentation of feeding volume after switch as "less than," "about the same as," or "more than" feeding volume achieved before switch
Feeding tolerance - gagging/retching
时间窗: Up to 30 days after formula switch
no change, tolerance improved, tolerance worsened
次要结局
- Protein intake(Up to 30 days after formula switch)
- Medication use(Prior to and up to 30 days following formula switch.)
- Caloric intake(Up to 30 days after formula switch)
- Weight(Prior to and up to 30 days following formula switch.)