NCT05990673尚未招募不适用
Determination of the 50% and 95% Effective Dose of Remimazolam for Intravenous Anesthesia Induction in Pediatric Patients
Zhihong LU0 个研究点目标入组 25 人开始时间: 2023年8月10日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 25
- 主要终点
- half effective dosage
研究概览
简要总结
Remimazolam has demonstrated the potential as a valuable medication for procedural sedation and general anesthesia. However, the effective dosage of remimazolam in pediatric patients is still unknown.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 3 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age from 3 to 12 years old
- •patients scheduled for surgery under general anesthesia
排除标准
- •American Society of Anesthesiologists status >=Ⅲ
- •Body mass index>=28kg/m2
- •patients who cannot cooperate with intravenous anesthesia induction
- •patients with risk of difficult airway
- •patients who are allergic to benzodiazepines
- •patients with delayed neurologic function
研究组 & 干预措施
remimazolam
Experimental
remimazolam is given for anesthesia induction
干预措施: Remimazolam (Drug)
结局指标
主要结局
half effective dosage
时间窗: from injection of remimazolam to loss of consciousness, at an average of 5 minutes
the dosage by which half of the patients will be sedated
次要结局
- 95% effective dosage(from injection of remimazolam to loss of consciousness, at an average of 5 minutes)
研究者
Zhihong LU
Associate professor
Air Force Military Medical University, China
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