NCT00947908Unknown不适用
Regulation of Blood Dendritic Cells During Immune Therapy for Hymenoptera Venom Allergy
University of Rostock2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2009年6月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Number of myeloid DC and plasmacytoid DC in peripheral blood
研究概览
简要总结
Dendritic cells (DC) play a key role in the pathogenesis of allergic diseases. The regulation of blood dendritic cells in patients with hymenoptera venom allergy before and during immune therapy is unknown.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 16 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with diagnosed hymenoptera venom allergy
- •No previous treatments for hymenoptera venom allergy
排除标准
- •Treatment with immunosuppressive agents
- •Any malignant disease
- •Infections within 1 week prior to the initiation of the treatment
结局指标
主要结局
Number of myeloid DC and plasmacytoid DC in peripheral blood
时间窗: Directly before, 1 hour after, and 12 months after initiation of immune therapy
次要结局
- Surface molecule expression on myeloid DC and plasmacytoid DC(Directly before, 1 hour after, and 12 months after initiation of immune therapy)
研究者
研究点 (2)
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