NCT02814240已完成不适用
Hepatic Steatosis and Pituitary Gland Failure, Evaluation by NMR Imaging
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 2
- 主要终点
- Measurement of liver fat mass by Magnetic Resonance Imaging (MRI)
研究概览
简要总结
The investigator put forward the hypothesis that liver fat mass in patients with pituitary gland failure is greater than that in a control population. Failure of the anterior pituitary and more particularly impaired production of growth hormone (GH) could be the principal mechanism responsible for increased liver fat mass in these patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who have provided consent
- •Patients over 18 years
- •Patients with pituitary disease (Pituitary adenoma, anterior pituitary failure, craniopharyngioma, empty sella syndrome, hypophysitis, infiltration of the stalk) requiring Magnetic Resonance Imaging (MRI) of the pituitary.
排除标准
- •Persons without national health insurance
- •Pacemaker (Contra-Indication for MRI)
- •Alcohol consumption greater than 4 glasses a day
- •Any treatment able to increase liver fat content (glitazones, systemic corticoids, immunosuppressants) are forbidden
- •Presence of metallic implants (Contra-Indication for MRI)
- •Claustrophobia
- •Adult under guardianship
- •Pregnant or breast-feeding women
- •Patients with a liver disease other than non-alcoholic steatosis
研究组 & 干预措施
Pituitary gland failure
Experimental
干预措施: fibroscan (Other)
Pituitary gland failure
Experimental
干预措施: NMR (Other)
Pituitary gland failure
Experimental
干预措施: Blood samples (Biological)
结局指标
主要结局
Measurement of liver fat mass by Magnetic Resonance Imaging (MRI)
时间窗: Measured at Day 0
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
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