Brain Bases of Visual Perceptionnatural Scenes of Natural Scenes.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 141
- 试验地点
- 2
- 主要终点
- Identify brain bases of natural scenes's visual perception of the natural scenes
研究概览
简要总结
Using the available data from psychophysics, cellular electrophysiology and functionnal neuroanatomy of visual pathway, current models of visual recognition suppose that the perception of scenes start with a parallel extraction of differents elementary visual characteristics to different spatial frequencies according to a default processing principle named : 'coarse-to-fine'.
According to this principle, the visual scene's analysis would be decomposed in two steps. Fisrt, the fast analysis of the global information borne by low frequency of the scene will provide an overview of the scene's structure and would enable a first perceptive categorisation which would be then refined, approved or denied by the latest analysis of the most local, detailed and precise information, carried by the very high spatial frequency of the scene.
The research carried out since several years is preparing a biologically plausible model and to find brain bases by different imaging techniques among healthy subjects but also patients with a brain lesion and patients with a peripheral lesion.
The main goal of this Magnetic Resonance Imaging study is to find brain bases of natural scenes's visual perception of the natural scenes.
Three studies in Magnetic Resonance Imaging will be conducted, during which subjects will have to categorize pictures of natural scenes filtered in spatial frequencies. The outcome of this study will allow to refine models of visual recognition, most of them based on analysis of spatial frequencies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 4 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •for young adults :
- •Subjet over 18 years and less than 30 years
- •Affiliation to a social security
- •Free signed consent
- •Medical exam done before participation to the study
- •Normal or corrected visual acuity
排除标准
- •four young adults :
- •Counter-argument to MRI
- •Pregnant, breast-feeding or parturient women
- •Adults non protected or unable to express their consent
- •Adults protected
- •Important earing or visual disorder
- •Neuropsychiatric disorder current or past passée ou présente (exept benign epilepsy)
- •Severe affection on a general level (cardiac, respiratory, hematologic, renal, hépatic, cancerous)
- •Drug treatment in progress (exept anti-epileptic drug) likely to de modulate brain activity
- •Inclusion Criteria for old adults :
- •Subjet over 50 years
- •Affiliation to a social security
- •Free signed consent
- •Medical exam done before participation to the study
- •Normal or corrected visual acuity
- •Exclusion Criteria four old adults :
- •Counter-argument to MRI
- •Pregnant, breast-feeding or parturient women
- •Adults non protected or unable to express their consent
- •Adults protected
- •Important earing or visual disorder
- •Neuropsychiatric disorder current or past passée ou présente (exept benign epilepsy)
- •Severe affection on a general level (cardiac, respiratory, hematologic, renal, hépatic, cancerous)
- •Drug treatment in progress (exept anti-epileptic drug) likely to de modulate brain activity
- •Inclusion Criteria for children :
- •Children between 4 and 12 years
- •Affiliation to a social security
- •Free signed consent
- •Medical exam done before participation to the study
- •Normal or corrected visual acuity
- •Exclusion Criteria four children :
- •Counter-argument to MRI
- •Important earing or visual disorder
- •Important development disorder and/or acquisitions identified by parents and/or school teachers
- •Neuropsychiatric disorder current or past passée ou présente (exept benign epilepsy)
- •Severe affection on a general level (cardiac, respiratory, hematologic, renal, hépatic, cancerous)
- •Drug treatment in progress (exept anti-epileptic drug) likely to de modulate brain activity
结局指标
主要结局
Identify brain bases of natural scenes's visual perception of the natural scenes
时间窗: About 80 minutes
Evaluation 1 = Visual tasks Experience 1 : Brain bases of spatial frequencies treatment Experience 2 : Brain bases of Computer to Film (CtF) natural scenes analysis MRI exam Experience 3 : Part of parahippocampal gyrus in Computer to Film (CtF) natural scenes analysis MRI exam About 30 minutes Evaluation 2 = Retinotopy : only adults that have shown activations inside occipital cortex during evaluation 1 MRI exam about 50 minutes
次要结局
未报告次要终点