NCT03132779Unknown1 期
Intralipid Related Effect on NKcells in Patients With Unexplained Recurrent Spontaneous Abortions
Ahmed Mohamed Bahaa Eldin Ahmed0 个研究点目标入组 34 人开始时间: 2017年5月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 发起方
- 入组人数
- 34
- 主要终点
- Change in NK cells activity after injection of intralipid
研究概览
简要总结
Evaluating the effect of intralipid on the natural killer cells
详细描述
This study will done on women with recurrent spontaneous abortions having increased NKCELLS activity and evaluate the effect of Intralipid on them after re-estimation of NKcells activity again after one week of Intralipid adminstration
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 38 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •All women icluded having recurrent spontaneous abortions equal or more than twice.
- •Alittle women having increased NKCELLS activity.
排除标准
- •Any other diseases causing miscarriage as autoimmune (lupus erythematosus or antiphospholipid antibodies syndrome )or endocrinopathy (diabetes mellitus, thyroid disorders and hyperprolactinaemia)or thrombophilia (factor v leiden mutation, protein c or s deficiency, prothrombin G20210A mutation, antithrombin III deficiency ) or abnormal karyotyping to one or both of parents or previous history of hormonal contraception or intrauterine device usage at last 3 months or any contraindications for intralipid usage.
研究组 & 干预措施
One armed
Experimental
One group of patient will take Intralipid for all
干预措施: Intralipid (Drug)
结局指标
主要结局
Change in NK cells activity after injection of intralipid
时间窗: One week
NK cells is measured before and after injection of intralipid and is noticed for change in activity
次要结局
未报告次要终点
研究者
Ahmed Mohamed Bahaa Eldin Ahmed
Clinical professor
Ain Shams Maternity Hospital
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