2024-517508-12-00招募中4 期
Infections after hysterectomy - a placebo controlled study comparing the profylactic use of azithromycin and cefuroxime with single cefuroxime
HUS-Yhtymae6 个研究点 分布在 1 个国家目标入组 2,278 人开始时间: 2024年10月24日最近更新:
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 2,278
- 试验地点
- 6
- 主要终点
- Deep wound and pelvic organ infections up to 30 days postoperatively
研究概览
简要总结
To study post-hysterectomy infections and to compare the use of azithromycin and cefuroxime vs single cefuroxime in antibiotic prophylaxis
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 65+ years（18-64 Years, 65+ Years）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women undergoing hysterectomy for a benign indication in a public hospital in Finland who have not any contraindications for azithromycin or cefuroxime. The person must understand the information given in finnish or swedish.
排除标准
- •Inability to understand the study protocol. Allergy for either cefuroxime or azithromycin. Congenital or acquired prolonged QTc interval. Use of medicines that may prolong QTc interval (class Ia arrhythmia medications, quinidine, procainamide, and class III arrhythmia medications dofetilidi, amiodarone and sotalol). Use of SSRI medication and prolonged QTc interval.
结局指标
主要结局
Deep wound and pelvic organ infections up to 30 days postoperatively
Deep wound and pelvic organ infections up to 30 days postoperatively
次要结局
- Surficial infections and other infections, such has urine tract infections, and fever over 38 ℃ over 2 days.
研究者
HUS Naistenklinikka
Scientific
HUS-Yhtymae
研究点 (6)
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