Instantaneous Wave-free Ratio and Fractional Flow Reserve Pullback Gradient to Guide Revascularization in Patients with Diffuse/tandem Coronary Lesions

Matsuo Hitoshi0 个研究点目标入组 300 人开始时间: 2020年8月24日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1.>20 years of age
•2.Willing to participate and able to understand, read, and sign the informed consent document before the planned procedure
•3.Eligible for coronary angiography and/or percutaneous coronary intervention
•4.Patient with at least 2 separate (>10mm apart) or diffuse (>20mm) de novo angiographically 50-90% stenoses in one native major epicardial vessel or their major branches (The stenosis will be regarded as single when the gap is 10mm or shorter between the 2 narrowings)
•5.Single coronary artery disease
•6.Stable coronary artery disease (with or without a history of PCI)

•1.Previous CABG with patent grafts to the interrogated vessel
•2.Total coronary occlusions
•3.Cardiogenic shock, or intra-aortic balloon pumping
•4.Contraindications to PCI or drug-eluting stent (DES) implantation
•5.Malignant disease with unfavorable prognosis that may influence survival within the next 3 years
•6.EF < 30%
•7.eGFR < 15mL/min/1.73m2
•8.Pregnant or planning to be pregnant
•9.Frequent arrhythmia
•10.Acute coronary syndrome or a history of myocardial infarction
•11.Severe valvular heart disease
•12.Distal coronary disease < 2.5 mm by visual estimation
•13.Baseline flow < TIMI 3 or intracoronary thrombus
•14.Included in other intervention trials
•15.Weight > 200kg
•16.Severe allergy to contrast media
•17.Contraindications to antithrombotic therapy

发起方

Matsuo Hitoshi