NCT00867789终止不适用
Trimethoprim-sulfamethoxazole Versus Placebo in the Treatment of Cutaneous Abscesses in the Emergency Department
Children's Mercy Hospital Kansas City1 个研究点 分布在 1 个国家目标入组 140 人开始时间: 2009年3月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- Health Outcomes After Use With Trimethoprim-sulfamethaxazole
研究概览
简要总结
The purpose of this study is to determine if there is a difference between an antibiotic, trimethoprim-sulfamethoxazole versus placebo in healing outcomes of soft tissue abscesses following incision and drainage.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 3 Months 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 3 months to 17 years
- •Single, localized soft tissue abscesses requiring incision and drainage with purulent material obtained
- •Diameter of the abscess less than 5cm as measured by the treating physician
排除标准
- •Signs of systemic illness or ill-appearing, as determined by the treating physician
- •Admission to the hospital following treatment in the Emergency Department
- •Known sulfa allergy
- •Immunocompromised patients
- •Soft tissue abscesses involving the perineum (labia, scrotum, penis, perirectal)
- •Previous antibiotic use (for any reason) in the past seven days
- •Non-English speaking patients and families
研究组 & 干预措施
Trimethoprim-sulfamethaxazole
Experimental
Incision and drainage of the abscess and treatment with oral TMP-SMX (100 patients)
干预措施: Trimethoprim-sulfamethoxazole (Drug)
Sugar pill
Placebo Comparator
Incision and drainage of the abscess and treatment with oral placebo (100 patients)
干预措施: Sugar pill (Drug)
结局指标
主要结局
Health Outcomes After Use With Trimethoprim-sulfamethaxazole
时间窗: two years
次要结局
未报告次要终点
研究者
研究点 (1)
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