NCT01269684撤回4 期
A 6-Month Open Pilot Study to Investigate the Safety and Tolerability of Immediate Conversion From Calcineurin Inhibitor Tacrolimus to Everolimus in Stable Maintenance Renal Transplant Recipients
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Routine safety laboratory
研究概览
简要总结
The purpose of this study is to investigate safety and tolerability of an immediate conversion from Tacrolimus to everolimus in stable renal allograft recipients.
Interest in developing CNI-free regimens using other agents such as the proliferation signal inhibitor everolimus.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
1
Experimental
Initial dose 1.5 mg b.i.d. Target blood trough level 4-10 ng/ml
干预措施: Everolimus (Drug)
结局指标
主要结局
Routine safety laboratory
时间窗: Month 6
次要结局
- renal function(Months 1, 2, 4 and 6)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
2 期
AMO-01 to Treat Adolescents and Adults With Phelan-McDermid Syndrome (PMS) and Co-morbid EpilepsyPhelan-McDermid SyndromeEpilepsyNCT03493607Alexander Kolevzon6
尚未招募
2 期
A pilot study to evaluate the feasibility, safety and tolerability of neoadjuvant triple therapy with zoledronic acid, docetaxel, and luteinising hormone-releasing hormone (LH-RH) analogue for men with high-risk prostate cancer to be treated by radical prostatectomyCancer - ProstateProstate cancerACTRN12607000082404rology Department The Royal Melbourne Hospital15
招募中
不适用
A pilot study of psychotherapeutic intervention for complex presentations of first-episode psychosisEarly psychosisMental Health - Psychosis and personality disordersBorderline Personality DisorderACTRN12605000594628Orygen Research Centre and Orygen Youth Health16
已完成
不适用
A preliminary study to examine and evaluate the effect of obeticholic acid (INT-747) for the treatment of portal hypertension in patients with alcoholic liver diseaseCirrhosisISRCTN22662520Intercept Pharmaceuticals Inc34
尚未招募
不适用
Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery DiseaseCoronary Artery DiseaseNCT06253884Indiana University30