Intramuscular corticosteroid injections in hip osteoarthritis: a double-blinded randomized controlled trial - HOCI study

Erasmus MC0 个研究点开始时间: 2011年5月11日最近更新: 2012年3月19日

适应症

试验速览

暂无简介。

•The inclusion criteria will be
•1. a diagnosis of OA of the hip according to the clinical ACR criteria, including radiologic evidence of OA (Kellgren-Lawrence (K-L) score ge 2)
•2. Age > 40 years
•3. Symptomatic disease for at least 6 months prior to enrolment
•4. Persistent pain despite receiving optimal doses of normal pain medication (acetaminophen (3 gr/day) and/or a NSAID) for at least 3 weeks. Pain severity (in rest or on walking) defined as a minimum score of 3 on NRS (0-10 range)
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•The exclusion criteria include local or systemic infection precluding injection, diabetes mellitus, systemic arthritis, allergy to corticosteroid agent, use of oral corticosteroids, coagulopathy, anticoagulant therapy (cumarine type), peptic ulcer, previous IA steroid injection into the index hip the past 6 months, radiologic signs of osteonecrosis, pregnancy, participation in other medical trials, and on the waiting list for a total hip arthroplasty.

发起方