Prevalence of Use of Anticoagulant, and Associated Factors of Anticoagulant Refusal in Non-valvular Atrial Fibrillation Patients---- A Study in Hong Kong General Out-patient Clinic
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- The prevalence of anticoagulant use in non-valvular atrial fibrillation patients
研究概览
简要总结
Atrial fibrillation is a clinically significant cardiac arrhythmia that increases the risk of stroke by 3 to 4 times. Oral anticoagulation has been shown to mitigate stroke risk by two-thirds among patients with AF and is widely recommended in optimizing AF management.Direct oral anticoagulants have also been demonstrated to be superior to warfarin with respect to the risk of fatal bleeding and stroke prevention.
However, the previous study finding highlighted a great gap between current guidelines and the clinical management of AF .Nonetheless, the decision for anticoagulant use is not straightforward.It is worth to investigate the updated prevalence of anticoagulant use, the reasons for not receiving anticoagulant, and the factors independently associated with anticoagulant refusal in patients with non-valvular atrial fibrillation.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis as atrial fibrillation
- •aged ≧18 years
- •able to given consent
排除标准
- •Unable/unwillingness to sign informed consent to study
- •mechanical heart valve
- •moderate-to-severe mitral stenosis
- •Transient atrial fibrillation from reversible cause (e.g., during respiratory tract infection or bronchospasm)
- •pregnancy
- •hospitalization within 1 month prior to inclusion in the study.
结局指标
主要结局
The prevalence of anticoagulant use in non-valvular atrial fibrillation patients
时间窗: August 2019 to March 2020
calculate the prevalence of anticoagulant use in non-valvular atrial fibrillation patients
次要结局
- the rate of the refusal of anticoagulant use(August 2019 to March 2020)
研究者
chen liujing
resident
Prince of Wales Hospital, Shatin, Hong Kong
