Provocation After Nurse-Directed Assessment (PANDA) Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 440
- 试验地点
- 4
- 主要终点
- Delabelling Success Rate
研究概览
简要总结
The study aims to evaluate the effectiveness and safety of a collaborative nurse-allergist approach in penicillin allergy delabeling services. It also seeks to assess the impact on patients' quality of life and compare resource utilization and cost-effectiveness between the nurse-allergist collaborative approach and the traditional allergist-led approach.
详细描述
This study hypothesizes that by involving both nurses and allergists in the delabeling process and categorizing patients based on risk levels, it will achieve comparable success rates, safety, and improvements in patients' quality of life. This approach is expected to offer superior advantages in terms of time efficiency, resource utilization, and cost-effectiveness compared to traditional allergist-led services.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Receiving inpatient or outpatient treatment at a participating hospital during the study period;
- •Possessing a documented penicillin allergy label;
- •Underwent penicillin allergy evaluation by the nurse-allergist collaborative approach or the traditional allergist-led approach
- •Demographic and clinical data required for the study available.
排除标准
- •Patients unable to provide a complete medication history or history of penicillin allergy;
- •Patients with only emergency or short-term treatment records;
- •Patients who have taken steroids, antihistamines, or similar medications within the last 3 days.
结局指标
主要结局
Delabelling Success Rate
时间窗: 6 months
Assess the proportion of low-risk patients who are no longer considered allergic to penicillin after delabeling.
次要结局
- Health-Related Quality of Life(6 months)
- Antibiotic Usage Rate(6 months)
- Age Group Analysis(6 months)
- Immunocompetence Status(6 months)
- Initial vs. Recurrent Labeling(6 months)
研究者
Prof. Sophia Siu-chee Chan
Prof.
The University of Hong Kong