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临床试验/NCT06836050
NCT06836050已完成不适用

The Effect of Intrapulmonary Percussive Ventilation (IPV) on Lung Compliance in Critically Ill Pediatric Patients Requiring Invasive Mechanical Ventilation.

Northwell Health2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年1月13日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
2
主要终点
Dynamic Compliance

研究概览

简要总结

The goal of this observational study is to determine if Intrapulmonary Percussive Ventilation (IPV) improves lung compliance in children receiving conventional invasive mechanical ventilation. The main questions it aims to answer are:

  1. Does IPV improve lung compliance 15 minutes after and 3 hours after receiving one treatment in a heterogeneous group of pediatric patients?
  2. Does IPV improve lung compliance in patients with Pediatric Acute Respiratory Distress Syndrome (PARDS), and what is the degree of change compared to those without PARDS?
  3. What is the effect of IPV on lung compliance according to PARDS severity (mild-moderate disease vs. severe disease).
  4. What is the incidence of adverse effects of IPV?

Participants will receive IPV because their medical team feels it will help their lung recovery and has already determined them to be safe candidates to receive this therapy, which is a standard airway clearance modality already routinely used in our PICU. Nothing additional will happen to participants as a result of this study. Enrolling in this study simply gives the study team permission to collect specific health information that identifies your child for research purposes, which may include results from medical tests found in their medical record and information from your child's bedside monitor and ventilator. This information will be collected before and after the IPV treatments to evaluate their response to the therapy.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
0 Days 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • ≤18 years old on conventional intermittent mandatory ventilation in the PICU that the physician deems is a candidate for IPV

排除标准

  • The inability to accurately obtain ventilator measurements

结局指标

主要结局

Dynamic Compliance

时间窗: Baseline (15 minutes before IPV treatment), 15 minutes after IPV treatment, and 3 hours after IPV treatment

A measurement calculated and obtained from the patient's ventilator, averaged over 1 minute.

次要结局

  • Static Compliance (when applicable)(Baseline (15 minutes before IPV treatment), 15 minutes after IPV treatment, and 3 hours after IPV treatment)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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