Evaluation of Conventional Collagen Crosslinking in Young Keratoconus.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 2
- 主要终点
- Change in Keratometric indices
研究概览
简要总结
Keratoconus is a chronic progressive non - inflammatory disorder characterised by progressive steepening and thinning of cornea and high myopic astigmatism, accounting for poor visual acuity in such individuals. Keratoconus seems to be more advanced on presentation, in young patients.
The investigators intend to evaluate the effectiveness of conventional collagen cross linking in young patients diagnosed with keratoconus.
详细描述
Keratoconus is progressive ectatic corneal disorder characterised by progressive corneal thinning, steep corneal curvatures and usually associated with high irregular myopic astigmatism.
The major problems concerning keratoconus in young patients are;
- Rapid rates of progression in young keratoconic corneas as compared to adults.
- Poor biomechanical properties of young corneas.
- Poor quality of vision, which predisposes to a very poor quality of life.
- High rates of complications and failure post keratoplasty in young patients.
The investigators intend to evaluate the effectiveness of conventional collagen crosslinking in young patients with keratoconus with regards to keratometric indices and visual acuity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 3 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 years and below.
- •Patients diagnosed to have keratoconus at presentation and willing for follow - up at regular intervals post treatment.
排除标准
- •Any disease causing abnormal topography other than keratoconus.
- •Any ocular condition predisposing towards poor vision (retinal , lens problems)
结局指标
主要结局
Change in Keratometric indices
时间窗: 1 months
The keratometric readings in the steepest and flattest meridians, along with the average K readings were compared pre and post treatment using conventional collagen cross linking technique at 1 month post cross linking.
次要结局
- Improvement in vision(12 months)
研究者
Dr.ANAND PARTHASARATHY, Dr. Ramesh Hariharan
Dr. Anand Parthasarathy
Vasan Eye Care Hospital