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临床试验/NCT03597308
NCT03597308已完成不适用

PROSPECTIVE RANDOMIZED CONTROLLED TRIAL COMPARING OXYCODONE, IBUPROFEN AND ACETAMINOPHEN AFTER WIDE AWAKE HAND SURGERY

Rothman Institute Orthopaedics1 个研究点 分布在 1 个国家目标入组 210 人开始时间: 2017年3月17日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
210
试验地点
1
主要终点
Numeric rating Scale for Pain

研究概览

简要总结

The purpose of the study is to evaluate the efficacy of three different types of pain medication (Oxycodone - an opioid, Ibuprofen - a non-steroidal anti-inflammatory, and Acetaminophen - a non-opioid analgesic) in the management of postoperative pain following single soft tissue procedures of the hand and wrist performed exclusively under local anesthesia without sedation. The results of this study will help define optimal prescribing guidelines following the two most common hand surgeries while also potentially validating the use of opioid alternatives post-operatively in order to help mitigate excessive or unnecessary dispensal of opioid analgesics.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

研究组 & 干预措施

Opioid Group

Active Comparator

干预措施: 5mg of Oxycodone every 6 hours as needed for pain (Drug)

NSAID group

Active Comparator

干预措施: 600mg of Ibuprofen every 6 hours as needed for pain (Drug)

Acetaminophen

Active Comparator

干预措施: 500mg of Acetaminophen every 6 hours as needed for pain (Drug)

结局指标

主要结局

Numeric rating Scale for Pain

时间窗: 2 weeks post-op

11-point numeric rating scale (NRS) for pain

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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