NCT03810287No Longer Available不适用
The Use Of Domperidone For The Relief Of Refractory Upper Gastrointestinal GI Symptoms
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- No Longer Available
- 试验地点
- 1
研究概览
简要总结
To prescribe oral domperidone for patients with upper GI symptoms who have failed or suffered adverse effects from standard medical therapy.
详细描述
The primary objective of this study is to prescribe oral domperidone for patients with upper GI symptoms who have failed or suffered adverse effects from standard medical therapy
研究设计
- 研究类型
- Expanded Access
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Males or females who are 18 years of age or older
- •Symptoms or manifestations secondary to Gastro esophageal reflux disease (GERD) (e.g., persistent esophagitis, heartburn, upper airway signs or symptoms or respiratory symptoms), gastrointestinal motility disorders such as nausea, vomiting, severe dyspepsia or severe chronic constipation that are refractory to standard therapy.
排除标准
- •i. History of, or current, arrhythmias including ventricular tachycardia, ventricular fibrillation and Torsade des Pointes. Patients with minor forms of ectopy (PACs) are not necessarily excluded.
- •ii. Clinically significant bradycardia, sinus node dysfunction, or heart block.
- •iii. Prolonged QTc (QTc>450 milliseconds for males, QTc>470 milliseconds for females)
- •iv. Clinically significant electrolyte disorders.
- •Gastrointestinal hemorrhage or obstruction.
- •Presence of a prolactinoma (prolactin-releasing pituitary tumor).
- •Pregnant or breast feedings female.
- •Known allergy to domperidone
研究者
研究点 (1)
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