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临床试验/ACTRN12622000300774
ACTRN12622000300774招募中未知

Characterisation of upper aerodigestive tract dysfunction in individuals with chronic cough

niversity of Canterbury0 个研究点目标入组 80 人开始时间: 2022年2月16日最近更新:
适应症

试验速览

阶段
未知
状态
招募中
发起方
入组人数
80

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Non-randomised trial
主要目的
Diagnosis
盲法
Open (masking not used)

入排标准

年龄范围
18 Years 至 o limit(—)
性别
All

入选标准

  • For the chronic cough group:
  • - 18 years and over
  • - Able to consent to study
  • - Frequent coughing lasting longer than eight weeks (Morice et al., 2020)
  • - Optimal management of chronic cough without resolution, prompting referring
  • respiratory physician to consider behavioural cough control therapy
  • For the healthy group:
  • - 18 years and over
  • - Able to consent to the study

排除标准

  • For the chronic cough group:
  • - Patient has not received sufficient prior assessment and/or treatment of chronic cough on respiratory physician's review of health information
  • - Structural abnormalities of the lower airways including emphysema, bronchiectasis, pulmonary fibrosis, or sarcoidosis
  • - Chronic obstructive pulmonary disease
  • - Smoking or vaping in the last 6 months
  • - Upper respiratory tract infection in the last two weeks
  • - Uncontrolled reflux
  • - Use of opioids in the last six months
  • - Use of ACE inhibitors in the last six months
  • - Current use of neuromodulatory medicines
  • - Use of spirometry is contraindicated
  • - Previous or current behavioural treatment for chronic cough by a Speech-Language Therapist or physiotherapist
  • - Arrived from overseas in the last 14 days
  • - Displaying symptoms of Covid-19 in the last 14 days
  • - Been in close physical contact with someone with a suspected or confirmed case of Covid-19 in the last 14 days
  • - Lack of full vaccination against Covid-19, or unable to prove full vaccination using My Vaccine Pass
  • - Allergy or intolerance to wheat or gluten
  • For the healthy group:
  • - History of frequent coughing lasting longer than eight weeks
  • Structural abnormalities of the lower airways including emphysema, bronchiectasis, pulmonary fibrosis, or sarcoidosis
  • - Chronic obstructive pulmonary disease
  • - Smoking or vaping in the last 6 months
  • - Upper respiratory tract infection in the last two weeks
  • - Uncontrolled reflux
  • - Use of opioids in the last six months
  • - Use of ACE inhibitors in the last six months
  • - Current use of neuromodulatory medicines
  • - Use of spirometry is contraindicated
  • - Arrived from overseas in the last 14 days
  • - Displaying symptoms of Covid-19 in the last 14 days
  • - Been in close physical contact with someone with a suspected or confirmed case of Covid-19 in the last 14 days
  • - Lack of full vaccination against Covid-19, or unable to prove full vaccination using My Vaccine Pass
  • - Allergy or intolerance to wheat or gluten

研究者

发起方
niversity of Canterbury

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